TDF switch effective in Asian chronic HBV patients

Switching therapy to tenofovir disoproxil fumarate (TDF) is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients.

Administration of TDF resulted in a sustained virological response in the majority of nucleos(t)ide analogue (NUC)-experienced patients after nearly 2 years of follow-up, report the researchers.

But the findings also showed that those with a high baseline level of hepatitis B virus (HBV) were significantly less likely to achieve a sustained virological response than patients with lower baseline levels.

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