Hepatitis B Increases Risk of Stomach Cancer


— Christine M. Kukka, Project Manager, HBV Advocate

Researchers have found higher rates of pancreatic and liver cancer in individuals infected with the hepatitis B virus (HBV), and now a new study finds a 50% increased risk of gastric (stomach) cancer among people with HBV.

According to the study published in the February 2015 issue of the British Journal of Cancer, Chinese researchers compared gastric cancer rates in a group of 580 HBV-infected individuals and a control group of 580 healthy individuals of similar age and gender.

People with chronic hepatitis B had gastric cancer rates that were about 49% higher than the control group. There were higher rates of gastric cancer even in patients with no family history of stomach cancer.

Even patients with resolved hepatitis B infections (who were negative for the hepatitis B surface antigen–HBsAg-negative)–remained at higher risk of gastric cancer than the control group.
"In addition, some synergistic effects between HBV infection and blood type A in gastric cancer were identified," researchers reported, noting that having blood type A appeared to also increase gastric cancer risk.

Researchers called for additional studies and research to determine why hepatitis B increased cancer in the digestive system.


Source: www.ncbi.nlm.nih.gov/pubmed/2569548

http://www.hbvadvocate.org/news/HBJ12.3.htm

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