CDC Experts Estimates 6.5 New Hepatitis B Infections for Every One Reported


— Christine M. Kukka, Project Manager, HBV Advocate


For every one case of hepatitis B infection that is reported to health authorities in the U.S., researchers predicts there are 6.5 unreported, new infections among adults, which resulted in an estimated 18,730 new hepatitis B infections nationwide in 2011.

New hepatitis B and C infections are notoriously difficult to count. The infections may not cause symptoms or sufficient side effects to prompt a newly-infected person to see a doctor. Even when liver damage symptoms are present, the doctor must diagnose it correctly, confirm the infection through blood tests, and then report it accurately to local health authorities.

Because so many viral hepatitis cases are missed, local health officials can miss outbreaks and they often lack the information they need to design effective prevention and treatment programs.

To try to tackle this information void, researchers from the U.S. Centers for Disease Control and Prevention's division of viral hepatitis crafted a model that incorporated how many new infections would have been:
They used the number of hepatitis cases reported to the National Notifiable Diseases Surveillance System in their estimates. Their formula represents an updated approach to estimating new infections. The last model developed was designed in the 1990s and depended on the experiences of blood transfusion recipients who developed viral hepatitis. These new estimates are lower than what has been used historically by CDC, but may be more accurate.

However, this model does not capture new hepatitis B infections that result from HBV-infected immigrants coming to the U.S.

"...These estimates should be viewed as the best that can be generated at this time to support surveillance, planning and prevention activities until better data sets or more sophisticated models can be developed," researchers wrote in the January edition of the American Journal of Public Health.
Their model also predicted:
Source: www.ncbi.nlm.nih.gov/pubmed/24432918

HBV Journal Review
Marcxh 1, 2014, Vol 11, no 3 

Labels: ,