New Type of Interferon Effective in Hepatitis B Trial

A new type of pegylated interferon, call peginterferon Lambda, caused a faster decline in HBV DNA and hepatitis B surface antigen than the standard pegylated interferon alfa-2a (Pegasys), according to results of a ground-breaking Phase 2 clinical trial presented at the 23rd Conference of the Asian Pacific Association for the Study of the Liver in early June.

The weekly Lambda injections in 80 hepatitis B patients proved equally effective as standard pegylated interferon alfa-2a (Pegasys) medication in spurring loss of the hepatitis B “e” antigen. There were no safety concerns or additional side effects resulting from Lambda treatment.

—Christine. M. Kukka, Project Manager, HBV Advocate


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